Tools built for gene synthesis.
GeneIOS is a comprehensive gene synthesis solution pairing the first of its kind suite of software with high quality reagents and oligonucleotides.
GeneIOS Version 2.1 is designed to enable any user to make synthetic genes up to 1kb in length, cloned into their vector in a single day.
Learn more about making genes with the GeneIOS technology Synthesis Guide(GeneIOS Manual.pdf)
Quickly analyze your sequence
The first application, GeneScreen, will quickly ascertain the synthesizability of any DNA sequence. GeneScreen searches for : Complementary repetitive elements, Direct repetitive elements Polynucleotide strings, Analysis is complete when the overall GC content of your sequence has been examined.
Control design and optimize your sequence
The second application, GenePerfect, is an optimization and design tool that works in concert with GeneScreen. You can remove elements and motifs that may slow or inhibit synthesis from any sequence, while allowing you to optimize a coding sequence for protein expression and improved DNA stability. Start with a DNA or amino acid sequence : Avoid additional restriction sites in your optimized sequence, Add tags and ribosome binding sites to your sequence, Add restriction sites for cloning your sequence, Enter motifs that should be avoided, Choose host codon usage
Oligonucleotide design and reaction conditions
With just a few clicks, design your own set of oligonucleotides that will assemble with high fidelity in an hour.